Publikationsliste
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High-throughput screening for cell binding and repulsion peptides on multifunctionalized surfaces
Sonnentag, S. J.; Jenne, F.; Orian-Rousseau, V.; Nesterov-Mueller, A.
2024. Communications Biology, 7 (1), Art.-Nr.: 870. doi:10.1038/s42003-024-06541-7 -
Targeting CD44 and other pleiotropic co-receptors as a means for broad inhibition of tumor growth and metastasis
Mehner, L.-M.; Munoz-Sagredo, L.; Sonnentag, S. J.; Treffert, S. M.; Orian-Rousseau, V.
2024. Clinical and Experimental Metastasis. doi:10.1007/s10585-024-10292-4 -
Quantitative live imaging reveals a direct interaction between CD44v6 and MET in membrane domains upon activation with both MET ligands, HGF and internalin B
Tannoo, R. M.; Richert, L.; Koschut, D.; Tomishige, N.; Treffert, S. M.; Kobayashi, T.; Mély, Y.; Orian-Rousseau, V.
2024. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1866 (1), Art.-Nr. 184236. doi:10.1016/j.bbamem.2023.184236 -
Identification of an imidazopyridine-based compound as an oral selective estrogen receptor degrader for breast cancer therapy
Pan, M.; Solozobova, V.; Kuznik, N. C.; Jung, N.; Graessle, S.; Gourain, V.; Heneka, Y. M.; Cramer von Clausbruch, C. A.; Fuhr, O.; Munuganti, R. S. N.; Maddalo, D.; Blattner, C.; Neeb, A.; Sharp, A.; Cato, L.; Weiss, C.; Jeselsohn, R. M.; Orian-Rousseau, V.; Bräse, S.; Cato, A. C. B.
2023. Cancer Research Communications, 3 (7), 1378–1396. doi:10.1158/2767-9764.CRC-23-0111 -
Automated high-throughput image processing as part of the screening platform for personalized oncology
Schilling, M. P.; El Khaled El Faraj, R.; Urrutia Gómez, J. E.; Sonnentag, S. J.; Wang, F.; Nestler, B.; Orian-Rousseau, V.; Popova, A. A.; Levkin, P. A.; Reischl, M.
2023. Scientific Reports, 13, Article no: 5107. doi:10.1038/s41598-023-32144-z -
Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
Trouvilliez, S.; Cicero, J.; Lévêque, R.; Aubert, L.; Corbet, C.; Van Outryve, A.; Streule, K.; Angrand, P.-O.; Völkel, P.; Magnez, R.; Brysbaert, G.; Mysiorek, C.; Gosselet, F.; Bourette, R.; Adriaenssens, E.; Thuru, X.; Lagadec, C.; de Ruyck, J.; Orian-Rousseau, V.; Le Bourhis, X.; Toillon, R.-A.
2022. Journal of Experimental & Clinical Cancer Research, 41 (1), Art.-Nr. 110. doi:10.1186/s13046-022-02314-4 -
Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behaviour in colon cancer
Xu, T.; Verhagen, M.; Joosten, R.; Sun, W.; Sacchetti, A.; Munoz Sagredo, L.; Orian-Rousseau, V.; Fodde, R.
2022. eLife, 11, Art.-Nr.: e82006. doi:10.7554/eLife.82006 -
Different Involvement of Vimentin during Invasion by Listeria monocytogenes at the Blood–Brain and the Blood–Cerebrospinal Fluid Barriers In Vitro
Banovic, F.; Schulze, S.; Abu Mraheil, M.; Hain, T.; Chakraborty, T.; Orian-Rousseau, V.; Moroniak, S.; Weiss, C.; Ishikawa, H.; Schroten, H.; Adam, R.; Schwerk, C.
2022. International Journal of Molecular Sciences, 23 (21), Art.Nr. 12908. doi:10.3390/ijms232112908 -
CD44 expressed by myeloid cells promotes glioma invasion
Ivanova, E. L.; Costa, B.; Eisemann, T.; Lohr, S.; Boskovic, P.; Eichwald, V.; Meckler, J.; Jugold, M.; Orian-Rousseau, V.; Peterziel, H.; Angel, P.
2022. Frontiers in Oncology, 12, Art.Nr. 969787. doi:10.3389/fonc.2022.969787 -
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop
Walter, R. J.; Sonnentag, S. J.; Munoz-Sagredo, L.; Merkel, M.; Richert, L.; Bunert, F.; Heneka, Y. M.; Loustau, T.; Hodder, M.; Ridgway, R. A.; Sansom, O. J.; Mely, Y.; Rothbauer, U.; Schmitt, M.; Orian-Rousseau, V.
2022. Cell death & disease, 13 (2), Art.-Nr.: 168. doi:10.1038/s41419-022-04607-0 -
A Guide to the Composition and Functions of the Extracellular Matrix
Karamanos, N. K.; Theocharis, A. D.; Piperigkou, Z.; Manou, D.; Passi, A.; Skandalis, S. S.; Vynios, D. H.; Orian-Rousseau, V.; Ricard-Blum, S.; Schmelzer, C. E. H.; Duca, L.; Durbee, M.; Afratis, N. A.; Troeberg, L.; Franchi, M.; Masola, V.; Onisto, M.
2021. The FEBS journal, 288 (24), 6850–6912. doi:10.1111/febs.15776 -
CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues
Yu, X.; Munoz-Sagredo, L.; Streule, K.; Muschong, P.; Bayer, E.; Walter, R. J.; Gutjahr, J. C.; Greil, R.; Concha, M. L.; Müller-Tidow, C.; Hartmann, T. N.; Orian-Rousseau, V.
2021. Blood, 138 (12), 1067–1080. doi:10.1182/blood.2020006343 -
Plasticity in Colorectal Cancer: Why Cancer Cells Differentiate
Walter, R. J.; Sonnentag, S. J.; Orian-Rousseau, V.; Munoz-Sagredo, L.
2021. Cancers, 13 (4), Art.Nr. 918. doi:10.3390/cancers13040918 -
BeadNet: Deep learning-based bead detection and counting in low-resolution microscopy images
Scherr, T.; Streule, K.; Bartschat, A.; Böhland, M.; Stegmaier, J.; Reischl, M.; Orian-Rousseau, V.; Mikut, R.
2020. Bioinformatics, 36 (17), 4668–4670. doi:10.1093/bioinformatics/btaa594 -
Combinatorial Synthesis of a Lipidoid Library by Thiolactone Chemistry: In Vitro Screening and In Vivo Validation for siRNA Delivery
Molla, M. R.; Chakraborty, S.; Munoz-Sagredo, L.; Drechsler, M.; Orian-Rousseau, V.; Levkin, P. A.
2020. Bioconjugate chemistry, 31 (3), 852–860. doi:10.1021/acs.bioconjchem.0c00013 -
CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity
Gutjahr, J. C.; Bayer, E.; Yu, X.; Laufer, J. M.; Höpner, J. P.; Tesanovic, S.; Härzschel, A.; Auer, G.; Rieß, T.; Salmhofer, A.; Szenes, E.; Haslauer, T.; Durand-Onayli, V.; Ramspacher, A.; Pennisi, S. P.; Artinger, M.; Zaborsky, N.; Chigaev, A.; Aberger, F.; Neureiter, D.; Pleyer, L.; Legler, D. F.; Orian-Rousseau, V.; Greil, R.; Hartmann, T. N.
2020. Haematologica, 106 (8), 2102–2113. doi:10.3324/haematol.2019.231944 -
Breast Cancer-Derived Microparticles Reduce Cancer Cell Adhesion, an Effect Augmented by Chemotherapy
Shechter, D.; Harel, M.; Mukherjee, A.; Sagredo, L. M.; Loven, D.; Prinz, E.; Avraham, S.; Orian-Rousseau, V.; Geiger, T.; Shaked, Y.; Wolfenson, H.
2020. Cells, 9 (10), 2269. doi:10.3390/cells9102269 -
Regulation of Staphylococcus aureus Infection of Macrophages by CD44, Reactive Oxygen Species, and Acid Sphingomyelinase
Li, C.; Wu, Y.; Riehle, A.; Orian-Rousseau, V.; Zhang, Y.; Gulbins, E.; Grassmé, H.
2018. Antioxidants & redox signaling, 28 (10), 916–934. doi:10.1089/ars.2017.6994 -
TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides
Bauer, J.; Rothley, M.; Schmaus, A.; Quagliata, L.; Ehret, M.; Biskup, M.; Orian-Rousseau, V.; Jackson, D. G.; Pettis, R. J.; Harvey, A.; Bräse, S.; Thiele, W.; Sleeman, J. P.
2018. Journal of molecular medicine, 96 (2), 199–209. doi:10.1007/s00109-017-1615-4 -
Differential recruitment of CD44 isoforms by ErbB ligands reveals an involvement of CD44 in breast cancer
Morath, I.; Jung, C.; Lévêque, R.; Linfeng, C.; Toillon, R.-A.; Warth, A.; Orian-Rousseau, V.
2018. Oncogene, 37, 1472–1484. doi:10.1038/s41388-017-0030-1 -
Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia
Gutjahr, J. C.; Szenes, E.; Tschech, L.; Asslaber, D.; Schlederer, M.; Roos, S.; Yu, X.; Girbl, T.; Sternberg, C.; Egle, A.; Aberger, F.; Alon, R.; Kenner, L.; Greil, R.; Orian-Rousseau, V.; Hartmann, T. N.
2018. Blood, 131 (12), 1337–1349. doi:10.1182/blood-2017-08-802462 -
Functional Genomic mRNA Profiling of Colorectal Adenomas : Identification and Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets
Hartmans, E.; Orian-Rousseau, V.; Matzke-Ogi, A.; Karrenbeld, A.; Groot, D. J. A. de; Jong, S. de; Dam, G. M. van; Fehrmann, R. S. N.; Nagengast, W. B.
2017. Theranostics, 7 (2), 482–492. doi:10.7150/thno.16816 -
A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer
Preca, B.-T.; Bajdak, K.; Mock, K.; Lehmann, W.; Sundararajan, V.; Bronsert, P.; Matzge-Ogi, A.; Orian-Rousseau, V.; Brabletz, S.; Brabletz, T.; Maurer, J.; Stemmler, M. P.
2017. OncoTarget, 8 (7), 11530–11543. doi:10.18632/oncotarget.14563 -
CD44v6-Peptide Functionalized Nanoparticles Selectively Bind to Metastatic Cancer Cells
Li, L.; Schmitt, M.; Matzke-Ogi, A.; Wadhwani, P.; Orian-Rousseau, V.; Levkin, P. A.
2017. Advanced science, 4 (1), Art.Nr. 1600202. doi:10.1002/advs.201600202 -
CD44 mediates the catch-bond activated rolling of HEPG2Iso epithelial cancer cells on hyaluronan
Hanke-Roos, M.; Fuchs, K.; Maleschlijski, S.; Sleeman, J.; Orian-Rousseau, V.; Rosenhahn, A.
2016. Cell adhesion & migration, 11 (5-6), 476–487. doi:10.1080/19336918.2016.1260809 -
CD44: More than a mere stem cell marker
Morath, I.; Hartmann, T. N.; Orian-Rousseau, V.
2016. International journal of biochemistry & cell biology, 81, 166–173. doi:10.1016/j.biocel.2016.09.009 -
Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress
Shatirishvili, M.; Burk, A. S.; Franz, C. M.; Pace, G.; Kastilan, T.; Breuhahn, K.; Hinterseer, E.; Dierich, A.; Bakiri, L.; Wagner, E. F.; Ponta, H.; Hartmann, T. N.; Tanaka, M.; Orian-Rousseau, V.
2016. Cell death & disease, 7, Article no: e2461. doi:10.1038/cddis.2016.342 -
Live cell imaging shows hepatocyte growth factor-induced Met dimerization
Koschut, D.; Richert, L.; Pace, G.; Niemann, H. H.; Mely, Y.; Orian-Rousseau, V.
2016. Biochimica et Biophysica Acta - Molecular Cell Research, 1863 (7), 1552–1558. doi:10.1016/j.bbamcr.2016.04.015 -
Fighting pancreatic cancer
Orian-Rousseau, V.
2016. Pan European Networks: Science and Technology, 18, 192–193 -
Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference with CD44v6 Signaling
Matzke-Ogi, A.; Jannasch, K.; Shatirishvili, M.; Fuchs, B.; Chiblak, S.; Morton, J.; Tawk, B.; Lindner, T.; Sansom, O.; Alves, F.; Warth, A.; Schwager, C.; Mier, W.; Kleeff, J.; Ponta, H.; Abdollahi, A.; Orian-Rousseau, V.
2016. Gastroenterology, 150 (2), 513–525e10. doi:10.1053/j.gastro.2015.10.020 -
CD44 regulates Wnt signaling at the level of LRP6
Orian-Rousseau, V.; Schmitt, M.
2015. Molecular & cellular oncology, 2 (3), e995046. doi:10.4161/23723556.2014.995046 -
Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6
Volz, Y.; Koschut, D.; Matzke-Ogi, A.; Dietz, M. S.; Karathanasis, C.; Richert, L.; Wagner, M. G.; Mély, Y.; Heilemann, M.; Niemann, H. H.; Orian-Rousseau, V.
2015. Bioscience reports, 35 (4), e00236. doi:10.1042/BSR20150093 -
Role of CD44 in tumor progression and metastasis
Matzke, A.; Sharirishvili, M.; Morath, I.; Orian-Rousseau, V.
2015. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, June 28 - July 1, 2014 Clinical and Experimental Metastasis, 32(2015) (Abstract) -
CD44 Plays a Functional Role in Helicobacter pylori-induced Epithelial Cell Proliferation
Bertaux-Skeirik, N.; Feng, R.; Schumacher, M. A.; Li, J.; Mahe, M. M.; Engevik, A. C.; Javier, J. E.; Peek, R. M.; Ottemann, K.; Orian-Rousseau, V.; Boivin, G. P.; Helmrath, M. A.; Zavros, Y.
2015. PLoS pathogens, 11 (2), 1–24/e1004663. doi:10.1371/journal.ppat.1004663 -
Paracrine met signaling triggers epithelial mesenchymal transition in mammary luminal progenitors, affecting their fate
Di-Cicco, A.; Petit, V.; Chiche, A.; Bresson, L.; Romagnoli, M.; Orian-Rousseau, V.; Vivanco, M.; Medina, D.; Faraldo, M. M.; Glukhova, M. A.; Deugnier, M. A.
2015. eLife, 4, e06104/1–25. doi:10.7554/eLife.06104 -
Perspectives of CD44 targeting therapies
Orian-Rousseau, V.; Ponta, H.
2015. Archives of toxicology, 89 (1), 3–14. doi:10.1007/s00204-014-1424-2 -
CD44 acts as a signaling platform controlling tumor progression and metastasis
Orian-Rousseau, V.
2015. Frontiers in immunology, 6 (154), 1–4. doi:10.3389/fimmu.2015.00154 -
CD44 functions in Wnt signaling by regulating LRP6 localization and activation
Schmitt, M.; Metzger, M.; Gradl, D.; Davidson, G.; Orian-Rousseau, V.
2015. Cell death and differentiation, 22, 677–689. doi:10.1038/cdd.2014.156 -
CD44 is a multidomain signaling platform that integrates extracellular matrix cues with growth factor and cytokine signals
Orian-Rousseau, V.; Sleeman, J.
2014. Advances in cancer research, 123, 231–254. doi:10.1016/B978-0-12-800092-2.00009-5 -
Endocytosis of Fgf8 is a double-stage process and regulates spreading and signaling
Rengarajan, C.; Matzke, A.; Reiner, L.; Orian-Rousseau, V.; Scholpp, S.
2014. PLOS ONE, 9 (1), e86373/1–11. doi:10.1371/journal.pone.0086373 -
Internalization of Met requires the co-receptor CD44v6 and its link to ERM proteins
Hasenauer, S.; Malinger, D.; Koschut, D.; Pace, G.; Matzke, A.; Au, A. von; Orian-Rousseau, V.
2013. PLoS one, 8 (4), e62357/1–15. doi:10.1371/journal.pone.0062357 -
Opposing effects of high- and low-molecular weight hyaluronan on CXCL12-induced CXCR4 signaling depend on CD44
Fuchs, K.; Hippe, A.; Schmaus, A.; Homey, B.; Sleeman, J. P.; Orian-Rousseau, V.
2013. Cell death & disease, 4, Art. Nr. e819. doi:10.1038/cddis.2013.364 -
The surface proteins InlA and InlB are interdependently required for polar basolateral invasion by Listeria monocytogenes in a human model of the blood-cerebrospinal fluid barrier
Gründler, T.; Quednau, N.; Stump, C.; Orian-Rousseau, V.; Ishikawa, H.; Wolburg, H.; Schroten, H.; Tenenbaum, T.; Schwerk, C.
2013. Microbes and Infection, 15, 291–01. doi:10.1016/j.micinf.2012.12.005 -
Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis
Meinecke, A. K.; Nagy, N.; D’Amico Lago, G.; Kirmse, S.; Klose, R.; Schrödter, K.; Zimmermann, A.; Helfrich, I.; Rundqvist, H.; Theegarten, D.; Anhenn, O.; Orian-Rousseau, V.; Johnson, R. S.; Alitalo, K.; Fischer, J. W.; Fandrey, J.; Stockmann, C.
2012. Blood, 119, 5931–5942. doi:10.1182/blood-2011-12-396895 -
c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice
Olaku, V.; Matzke, A.; Mitchell, C.; Hasenauer, S.; Sakkaravarthi, A.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2011. Molecular Biology of the Cell, 22, 2777–2786. doi:10.1091/mbc.E11-02-0134 -
CD44, a therapeutic target for metastasising tumours
Orian-Rousseau, V.
2010. European journal of cancer, 46 (7), 1271–77. doi:10.1016/j.ejca.2010.02.024 -
A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis
Tremmel, M.; Matzke, A.; Albrecht, I.; Laib, A. M.; Olaku, V.; Ballmer-Hofer, K.; Christofori, G.; Heroult, M.; Augustin, H. G.; Ponta, H.; Orian-Rousseau, V.
2009. Blood, 114, 5236–44. doi:10.1182/blood-2009-04-219204 -
Involvement of CD44v6 in InIB-dependent Listeria invation
Jung, C.; Matzke, A.; Niemann, H. H.; Schwerk, C.; Tenenbaum, T.; Orian-Rousseau, V.
2009. Molecular Microbiology, 72, 1196–1207. doi:10.1111/j.1365-2958.2009.06716.x -
CD44v6 peptides block metastasis and interfere with angiogenesis
Matzke, A.; Tremmel, M.; Jannasch, K.; Albrecht, I.; Alves, F.; Ballmer-Hoffer, K.; Christofori, G.; Ponta, H.; Orian-Rousseau, V.
2008. 3rd European Conf.on Tumor Angiogenesis and Antiangiogenic Therapy (ECTA 2008), Padova, I, November 6-8, 2008 -
Haploinsufficiency of c-Met in CD44-/- mice identifies a collaboration of CD44 and c-Met in vivo
Matzke, A.; Sargsyan, V.; Holtmann, B.; Aramuni, G.; Asan, E.; Sendtner, M.; Pace, G.; Howells, N.; Zhang, W.; Ponta, H.; Orian-Rousseau, V.
2007. Molecular and Cellular Biology, 27, 8797–8806. doi:10.1128/MCB.01355-07 -
The co-receptor function of CD44v6 for c-Met and for VEGFR2 in angiogenesis
Tremmel, M.; Kastilan, T.; Pace, G.; Matzke, A.; Ponta, H.; Orian-Rousseau, V.
2007. Vortr.: Paul Scherrer Institut, Villigen, CH, 20.März 2007 -
CD44v6 peptides block metastatic spreading
Matzke, A.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. 4th IRCC Internat.Cancer Conf., Torino, I, June 7-9, 2007 Molecular Cancer Therapies : New Challenges and Horizons ; Beatson Internat.Cancer Conf., Glasgow, GB, June 17-20, 2007 -
Contribution of CD44v6 for c-Met activation and signaling: the co-receptor binds HGF and acts as an active organizer of a signalosome complex
Matzke, A.; Kastilan, T.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. Gordon Research Conf.’Mechanisms of Cell Signalling’, Oxford, GB, September 16- 21, 2007 -
Cancer stem cell: Redefining cancer
Orian-Rousseau, V.
2007. Vortr.: Universität Karlsruhe, 2.Juli 2007 -
CD44v6 and c-Met co-operate in synaptogenesis and in metastasis formation
Matzke, A.; Aramuni, G.; Sargsyan, V.; Zhang, W.; Holtmann, B.; Sendtner, M.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. 4th IRCC Internat.Cancer Conf., Torino, I, June 7-9, 2007 -
c-Met activation and signaling depends on CD44v6. The co-receptor organises a signalsome complex containing F-actin
Orian-Rousseau, V.; Kastilan, T.; Pace, G.; Matzke, A.; Ponta, H.
2007. BRECOSM Breast Cancer and Metastasis Conf., Paris, F, June 22-24, 2006 -
The role of CD44v6 as a co-receptor for c-Met
Matzke, A.; Kastilan, T.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. FASEB Summer Research Conf., Tucson, Ariz., August 11-16, 2007 -
Ras activation by Sos requires F-actin bound to ERMs
Orian-Rousseau, V.; Matzke, A.; Pace, G.; Kastilan, T.; Olaku, V.; Ponta, H.
2007. Beatson Internat.Cancer Conf., Glasgow, GB, June 18-21, 2006 -
The Co-receptor function of CD44v6 for RTKs
Orian-Rousseau, V.; Matzke, A.; Pace, G.; Kastilan, T.; Linfeng, C.; Ponta, H.
2007. BRECOSM Breast Cancer and Metastasis Conf., Paris, F, June 22-24, 2006 -
CD44v6 acts as co-receptor for c-Met. Ras activation by Sos requires F-actin bound to ERMs
Orian-Rousseau, V.; Matzke, A.; Pace, G.; Kastilan, T.; Okalu, V.; Ponta, H.
2007. Growth Factors and Signalling : Gordon Research Conf., Connecticut College, New London, Conn., July 16-21, 2006 -
The coreceptor function of CD44v6 for c-Met accounts for metastasis
Matzke, A.; Olaku, V.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. FASEB Summer Research Conf., Tucson, Ariz., August 11-16, 2007 Molecular Cancer Therapies : New Challenges and Horizons ; Beatson Internat.Cancer Conf., Glasgow, GB, June 17-20, 2007 -
The coreceptor function of CD44v6 in angiogenesis
Tremmel, M.; Linfeng, C.; Matzke, A.; Orian-Rousseau, V.; Ponta, H.
2007. 4th Internat.Kloster Seeon Meeting ’Angiogenesis’, Kloster Seeon, September 16- 19, 2006 -
New players in signal transduction: ERM proteins, F-actin and CD44
Hasenauer, S.; Matzke, A.; Kastilan, T.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. Spring 2007 Meeting : A Joint Meeting of the Genetics Society and the British Societies for Cell and Developmental Biology, Edinburgh, GB, March 29 - April 1, 2007 -
CD44v6 peptides block metastatic spreading and interfere with angiogenesis
Tremmel, M.; Matzke, A.; Ponta, H.; Orian-Rousseau, V.
2007. The Tumor-Vessel Interface : Internat.Symp., Kloster Seeon, September 22-25, 2007 -
The coreceptor function of CD44v6 for c-Met accounts for metastasis
Matzke, A.; Pace, G.; Ponta, H.; Orian-Rousseau, V.
2007. Gordon Research Conf.’Mechanisms of Cell Signalling’, Oxford, GB, September 16-21, 2007 -
CD44 v6 - a co-receptor in angiogenesis
Tremmel, M.; Matzke, A.; Albrecht, I.; Christofori, G.; Rothley, M.; Sleeman, J.; Ponta, H.; Orian-Rousseau, V.
2007. 4th Internat.Kloster Seeon Meeting ’Angiogenesis’, Kloster Seeon, September 16-19, 2006 -
Von der Grundlagenforschung zur Entwicklung metastasenspezifischer Peptide
Ponta, H.; Orian-Rousseau, V.
2007. Nachrichten - Forschungszentrum Karlsruhe, 39, 123–27 -
Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actin
Orian-Rousseau, V.; Morrison, H.; Matzke, A.; Kastilan, T.; Pace, G.; Herrlich, P.; Ponta, H.
2007. Molecular Biology of the Cell, 18, 76–83. doi:10.1091/mbc.E06-08-0674 -
Molekulare Mechanismen in Tumormetastasierung: Kooperation von Adhäsionsproteinen und Rezeptortyrosinkinase. Habilitation
Orian-Rousseau, V.
2006. Universität Karlsruhe (TH) -
A five-amino-acid peptide blocks Met and Ron dependent cell migration
Matzke, A.; Herrlich, P.; Ponta, H.; Orian-Rousseau, V.
2005. ELSO Meeting (European Life Scientist Organization), Dresden, September 3-6, 2005 -
A five-amino-acid peptide blocks Met- and Ron-dependent cell migration
Matzke, A.; Herrlich, P.; Ponta, H.; Orian-Rousseau, V.
2005. Cancer Research, 65, 6105–10 -
Genes upregulated in a metastasizing human colon carcinoma cell line
Orian-Rousseau, V.; Mink, S.; Mengwasser, J.; HogenEsch, H.; Guo, F.; Thies, W. G.; Hofmann, M.; Herrlich, P.; Ponta, H.
2005. International Journal of Cancer, 113, 699–705. doi:10.1002/ijc.20644 -
CD44v6 is a co-receptor for another member of the c-Met family, RON
Matzke, A.; Herrlich, P.; Ponta, H.; Orian-Rousseau, V.
2004. 2nd Internat.DFG Symp.’Cell Migration in Development and Disease’, Karlsruhe, October 10-13, 2004 -
The co-receptor function of CD44v6 towards c-Met in vitro and in vivo
Orian-Rousseau, V. M.; Kastilan, T.; Herrlich, P. A.; Ponta, H.
2004. 2nd Internat.DFG Symp.’Cell Migration in Development and Disease’, Karlsruhe, October 10-13, 2004 -
Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes
Machner, M. P.; Frese, S.; Schubert, W. D.; Orian-Rousseau, V.; Gherardi, E.; Wehland, J.; Niemann, H. H.; Heinz, D. W.
2003. Molecular Microbiology, 48, 1525–1536 -
CD44, un regulateur de la croissance et de l’invasion cellulaire
Orian-Rousseau, V.
2003. M S - Medecine Sciences, 19, 405–407 -
CD44 is required for two consecutive steps in HGF/c-Met signalling
Orian-Rousseau, V.; Chen, L.; Sleeman, J. P.; Herrlich, P.; Ponta, H.
2002. Genes and Development, 16, 3074–86 -
Stop or go - CD44 als Regulator essentieller zellulärer Entscheidungen
Ponta, H.; Orian-Rousseau, V.; Chen, L.; Morrison, H.; Herrlich, P.
2002. Nachrichten - Forschungszentrum Karlsruhe, 34, 36–40 -
Two opposite functions of CE44 in cancer
Orian-Rousseau, V.; Morrison, H.; Linfeng, C.; Ponta, H.; Herrlich, P.
2001. 6th World Congress on Advances in Oncology, Creta Maris, GR, October 18-20, 2001 -
Two sides of one and the same molecule, CD44: tumor metastasis promotion and suppression
Herrlich, P.; Morrison, H.; Linfeng, C.; Orian-Rousseau, V.; Ponta, H.
2001. 2001 Annual Scientific Conf.of the General Motors Cancer Research Foundation (GMCRF), ’Mechanisms of Metastasis’, Bethesda, Md., June 5-6, 2001 -
CD44 acts both as a growth- and invasiveness-promoting molecule and as a tumor-suppressing cofactor
Herrlich, P.; Morrison, H.; Sleeman, J.; Orian-Rousseau, V.; König, H.; Weg-Remers, S.; Ponta, H.
2000. Colorectal Cancer: New Aspects of Molecular Biology and Immunology and Their Clinical Applications, Berlin, October 8-9, 2000 Annals of the New York Academy of Sciences, 910(2000) -
CD44 acts both as a growth- and invasiveness-promoting molecule and as a tumor-suppressing cofactor
Herrlich, P.; Morrison, H.; Sleeman, J.; Orian-Rousseau, V.; König, H.; Weg-Remers, S.; Ponta, H.
2000. Annals of the New York Academy of Sciences, Colorectal Cancer: New Aspects of Molecular Biology and Immunology and Their Clinical Applications, Berlin, October 8-9, 2000, 910, 106–20